Chronic exposure may lead to severe damage to dopaminergic and serotoninergic neurons.Įvan Riddle, Annette Fleckenstein, in xPharm: The Comprehensive Pharmacology Reference, 2007Īctedron actemin adipan aktedrin aktedron alentol allodene alpha amphetamine alpha methylphenethylamine alphamethylphenylethylamine amfetamine 2 amino 1 phenylpropane amphamed amphamine amphetaime amphetamin amphetamine base phosphate amphetaminebase sulfate amphetamine detection amphetamine hydrochloride amphetamineintoxication amphetamine metabolism amphetamine phosphate amphetaminesulfate amphetamine toxicity amphetaminyl amphethamine amphezamin anara astedin badrin benzafinyl benzebar benzedrine benzolone benzpropamin benzpropamine beta aminopropylbenzene betafen beta phenyl isopropylamine beta phenylisopropylamine bluzedrin centramine delta amphetamine desoxynorephedrin dextro levo alpha methylphenethylamine dextro levoamphetamine dextrolevo amphetamine dextro levo 2 methylphenethylamine dextro levo 2 methylphenetylamine diethamine diethanine dipan d lamphetamine elastonin elastonon euphobine euphodine euphodyn fabedrine fenara fenedrin ibiozedrine isoamin isoamine isoamyn isoamyne isomyn l amphetamine levamfetamine levamphetamine levedrine levo amphetamine levoamphetamine levo amphetamine sulphate linampheta mecodrin mimetina monetamin monophos noclon norephedrane norphedrane novydrine obesinandromacro oktedrin oraldrina ortedrine percomon pharmamedrine pharmedrine phenamin phenedrine phenoprominum phenpromin 1 phenyl 2 aminopropane phenylaminopropane (phenylisopropyl) amine (phenylisopropyl)amine phenylisopropylamine 1 phenyl 2 propanamine profamina profetamine propisamine psychedrin psychedrine psychoton racemic desoxy norephedrine racemicdesoxy norephedrine racephen raphetamine rhinalator sedolin simpamina simpamine simpatedrin simpatedrine stimulan sympametin sympamine sympatedrine theptine vapedrine zedrin zedrine 1-Methyl-2-phenyl-ethylamine 1-Methyl-2-phenyl-ethylamine Amphetamine actedron adderall adderall xr alpha methylphenylethylamine amphetamine base sulfate amphetamine intoxication amphetamine sulfate d l amphetamine dextro levo amphetamine obesin andromacro obetrol phenyl isopropylamine racemic desoxy nor ephedrine
Methamphetamine has a high potential for abuse. Methamphetamine has effects similar to amphetamine, although CNS effects are more pronounced and peripheral ones are less prominent. The acute toxic effects of amphetamine (tremor, irritability, insomnia, confusion, anxiety, delirium, and hallucinations) are extension of the pharmacological effects and may be due to an increased release of serotonin from nerve terminals, or to direct effects on serotoninergic neurons. Most of amphetamine's effects are believed to be due to its ability to stimulate the release of biogenic amines (norepinephrine and dopamine) from their storage sites in the nerve terminals.
Main effects of acute administration are wakefulness, decreased sense of fatigue, elevation of mood, and increased ability to concentrate.
Aschner, in Encyclopedia of the Neurological Sciences (Second Edition), 2014 AbstractĪmphetamine has powerful central nervous system (CNS) stimulant actions, in addition to peripheral actions typical of indirect sympathomimetic drugs.
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